======================================================================================================================
DIALYSATE SODIUM AS AN OSMOTIC AGENT — can it buy back glucose?
======================================================================================================================

  sigma_Na = 0.050 vs sigma_glucose = 0.049 — nearly identical, so per osmole sodium pulls as hard as
  dextrose, and being an electrolyte it carries an anion with it (~2 mOsm per mmol/L added).
  The question is how much dextrose that saves BEFORE serum sodium reaches the 145 mmol/L ceiling.
  The shipped operating point is withheld (pending patent matter). Horizon 30 days.
  [REDACTED 2026-08-20: this line named two controller set-points with their values. This
   log is copied verbatim into the published site, so the header published them. Only this
   metadata line was changed; every measured row below is exactly as the run produced it.
   Unredacted original kept locally as na_for_glucose.log.pre_redaction (never published).]


======================================================================================================================
P4_anuric   (72 kg, urine 0.0 L/day, eGFR fraction 0.0)
======================================================================================================================
  dialysate Na    serum Na   peak Na   glucose abs   vs base   cum UF    dW     HCO3    outcome
  center / max     mmol/L    mmol/L        g/day         %       L      L      mmol/L
    136 / 142        143.0     143.1          196      +0.0     59.8  -0.04    18.9   ok
    140 / 146        143.4     143.6          187      -4.4     67.5  -0.04    18.6   ok
    144 / 150        143.9     144.0          179      -8.8     75.1  -0.04    18.4   ok
    148 / 154        144.3     144.5          170     -13.1     82.6  -0.06    18.2   ok
    152 / 158        144.8     144.9          163     -17.0     90.4  -0.26    18.0   ok
    156 / 162        145.3     145.4          156     -20.2     98.4  -0.68    17.8   OVER Na ceiling (peak 145.4)

======================================================================================================================
P1_typical_M70   (70 kg, urine 0.5 L/day, eGFR fraction 0.6)
======================================================================================================================
  dialysate Na    serum Na   peak Na   glucose abs   vs base   cum UF    dW     HCO3    outcome
  center / max     mmol/L    mmol/L        g/day         %       L      L      mmol/L
    136 / 142        143.2     143.2          180      +0.0     45.5  -0.65    19.0   ok
    140 / 146        143.7     143.8          175      -3.0     54.2  -1.08    18.8   ok
    144 / 150        144.3     144.4          170      -5.4     62.9  -1.65    18.5   ok
    148 / 154        144.8     145.0          168      -6.8     71.9  -2.49    18.3   ok
    152 / 158        145.4     145.5          166      -7.7     80.8  -3.31    18.0   OVER Na ceiling (peak 145.5)
    156 / 162        146.0     146.1          165      -8.4     89.5  -4.01    17.8   OVER Na ceiling (peak 146.1)

======================================================================================================================
VERDICT
======================================================================================================================
  P4_anuric          best usable dialysate Na 152: glucose 196 -> 163 g/day (-17.0%), serum Na peak 144.9
  P1_typical_M70     best usable dialysate Na 148: glucose 180 -> 168 g/day (-6.8%), serum Na peak 145.0

  READ IT THIS WAY. A large negative percentage in the best usable arm means the lever WORKS and the
  envelope is worth changing and retraining on. A small or positive one means sodium's low
  reflection coefficient lets it equilibrate away before it can do osmotic work, and the glucose
  exposure has to be addressed some other way. Either result is worth having before spending a
  retrain on it.